The Champions League group stage reaches the halfway point this week and Tuesday provides another set of tasty fixtures.

Liverpool travel to Atletico Madrid seeking revenge two seasons on from their last-16 exit to Diego Simeone's side in the pick of the games.

Real Madrid and Manchester City are each looking to respond to defeats last time out when they take on Shakhtar Donetsk and Club Brugge respectively.

Elsewhere, Paris Saint-Germain host RB Leipzig and two of Europe's great entertainers in Ajax and Borussia Dortmund face off in Amsterdam.

Here, Stats Perform takes a look at the key Opta data ahead of some key contests.

 

Atletico Madrid v Liverpool: Reds face bogey side

Following their last-16 exit to Atletico two seasons ago, Liverpool are winless in four Champions League meetings with the LaLiga champions – only Basel have they faced as many times without winning in Europe's top competition.

The Reds have also lost six of their past seven games on Spanish soil in the tournament since beating Real Madrid in the 2008-09 last 16, though they were victorious at the Wanda Metropolitano against Tottenham in the 2018-19 final.

Mohamed Salah opened the scoring in that meeting with Spurs and he has more recently scored in each of his past five away games for Liverpool in the Champions League – the longest-such streak by a Reds player in the competition.

Shakhtar Donetsk v Real Madrid: Will Ancelotti be Los Blancos' lucky omen?

Shakhtar beat Madrid home and away in the group stage last season and could become just the third side to win three in a row against Los Blancos in the competition after Bayern Munich and Juventus.

While Madrid's recent record against the Ukrainian outfit is poor, head coach Carlo Ancelotti has won all four of his previous Champions League games against Shakhtar – only against Bayern (six) and Liverpool (five) has he won more often.

Prior to their shock defeat at the hands of Sheriff last time out, Madrid beat Inter 1-0 at San Siro in their opening Group D contest. However, not since 2014-15 have they won their opening two Champions League away games.

 

Paris Saint-Germain v RB Leipzig: History not on Germans' side

After netting in PSG's win against Manchester City three weeks ago, Messi is looking to join Neymar (2017), Alex (2012) and George Weah (1994) in scoring in his first two home games for the club in the competition.

PSG have a great record against German opponents, having won seven of their eight meetings with Bundesliga clubs on home soil, though the exception in that run was in April this year when Bayern won 1-0 at the Parc des Princes.

The Ligue 1 side do not tend to slip up at home in the group stage, losing just one of their past 28 such games – against Manchester United in October 2020 – and netting 2.7 goals per game on average.

Club Brugge v Manchester City: Pep seeking response to Paris pain

Ahead of this first ever meeting with City, Brugge are winless in 12 matches against English opponents in all European competitions since beating Chelsea in the Cup Winners' Cup 26 years ago.

The Belgian champions are unbeaten in their past four home group matches in the Champions League, though, picking up eight points across that run – only once have they gone five in a row without defeat (a run of six that ended in October 2019).

But Pep Guardiola will be confident of City getting their campaign back on track following defeat in Paris, the Catalan coach having lost successive away games in the competition once previously when in charge of Bayern in 2014-15 (against Porto and Barcelona).

 

Other fixtures:

Ajax v Borussia Dortmund

2 - Dortmund have won their previous two major European matches in the Netherlands, both in the Champions League. Their last defeat on Dutch soil was in the 2002 UEFA Cup final against Feyenoord.

3 - Ajax are aiming to win their opening three games to a Champions League campaign for the first time since 1995-96 under Louis van Gaal, the season in which they last made it all the way to the final.


Besiktas v Sporting CP

4 - Sporting have failed to win a European match on Turkish soil, drawing three times and losing once, with that loss coming against Istanbul Basaksehir in February 2020 in the Europa League. Besiktas, though, have won just once in 11 home Champions League games, beating RB Leipzig 2-0 in September 2017.

3 - Sporting lost their opening two group matches, against Dortmund and Ajax, and are at risk of losing three in a row for the first time in the current group-stage format.


Porto v Milan

6 - Porto have kept a clean sheet in six of their past seven games in the group stage of the Champions League, though they did concede five times in their last outing in the competition against Liverpool.

7 - Including qualifying matches, seven of Milan's eight away matches in UEFA competitions in Portugal have ended as a draw, with their only win coming against Porto in March 1993 courtesy of a Jean-Pierre Papin goal.


Inter v Sheriff

- Inter have failed to score in their previous three home Champions League games (the last two group games in 2020-21 and against Madrid this term). They have never previously gone four major UEFA European home games without scoring.

- Sheriff are looking to become just the third team this century to win their first three games in the Champions League, after Leicester City in 2016-17 and Malaga in 2012-13.

Lionel Messi is in line to make his 150th Champions League appearance and his first with Paris Saint-Germain on Wednesday.

Mauricio Pochettino's men travel to Club Brugge and Messi is about to partake in his first European campaign without Barcelona, while Manchester City host RB Leipzig.

Liverpool and Milan renew rivalries in the competition for just the second time since the 2004-05 final between the pair but the Serie A side have a woeful record against English teams.

Inter have a similarly poor record against Spanish teams and they face Real Madrid, with Karim Benzema edging towards another goalscoring landmark.

Here, Stats Perform takes a look at the key Opta data ahead of Wednesday's fixtures.

Inter v Real Madrid: Benzema looks to edge past former Galactico Raul 

Inter have lost four of their last five against Real Madrid but Los Blancos have only won one of their previous eight away games against Wednesday's opponents as they prepare for a replay of last year's group stage outing.

However, Inter have not won against a Spanish team in Europe's premier competition since 2010 and Madrid have been victorious in 12 of their last 13 against Serie A outfits.

Carlo Ancelotti has Karim Benzema among his ranks and the forward will appear in his 17th consecutive campaign as he looks for his 72nd goal to move ahead of Raul (71) into fourth in the all-time scoring list.

 

Manchester City v RB Leipzig: Guardiola's group stage dominance

Manchester City are unbeaten in their last 17 group-stage ties and, since Pep Guardiola was appointed, they have lost just three of 30 at this stage of the competition.

The hosts are eyeing their 50th win in their 91st game as they look to become the second fastest to the half-century, while RB Leipzig have lost three of their last four against English opposition.

City's attacking riches could thrive at Etihad Stadium, too, Ferran Torres has scored four in his last six appearances in Europe - a goal every 90 minutes - and Riyad Mahrez has been involved in 22 goals in 28 starts for Leicester City and his current side in the Champions League.

 

Liverpool v Milan: Istanbul replay ends Rossoneri's seven-year wait

Milan will appear in their first Champions League since 2014, their first fixture a replay of the memorable 2004-05 final that saw Liverpool triumph.

Stefano Pioli's men have won just one of their last 13 against English opponents in European competition, while the Reds have lost just one of their last 12 group-stage games at Anfield in Europe under Jurgen Klopp.

Mohamed Salah (25) is one of two Liverpool players – along with Steven Gerrard (21) – to score 20+ times in the competition but Sadio Mane (19) could join them with a goal on Wednesday to become the fourth African to the 20-goal mark.

 

Club Brugge v Paris Saint-Germain: Pochettino's attacking riches

Paris Saint-Germain have netted 21 goals across six games against Belgian opposition – winning five and drawing once – while Club Brugge have only won one of their six opening games.

Lionel Messi – the second all-time leading scorer in the competition – could make his first PSG continental appearance, having scored 120 goals and provided 35 assists in 149 games for Barcelona against teams from 17 nations.

The visitors also boast half of the six players to be involved in 30+ goals in the competition in the last four seasons, with Kylian Mbappe (37), Messi (36) and Neymar (31) all doing so.

Other fixtures:

Atletico Madrid v Porto:

41 – Diego Simeone has won 41 of the 79 Champions League fixtures he has managed since 2013-14, with only Pep Guardiola (56) picking up more wins in this period.

4 – Porto have won four of their last five away games in the competition, their only loss coming against eventual runners-up Manchester City last term.

Besiktas v Borussia Dortmund:

1 – Besiktas have only collected one win in their last 10 home games in the Champions League and two of four defeats in that run have come against Bundesliga sides.

100 – Borussia Dortmund have a 100 per cent record against Turkish opposition in the Champions League, though all four wins have come against Galatasaray.

Sheriff Tiraspol v Shakhtar Donetsk:

1 – Sheriff Tiraspol are the first ever Moldovan team to feature in the Champions League proper. They are unbeaten in their last nine in European competition.

3 – Shakhtar Donetsk have only been beaten three times in their last 11 games as they went unbeaten against Real Madrid and Inter in the group stages last season.

Sporting CP v Ajax:

36 – Aged just 36, Ruben Amorim becomes the second youngest Portuguese manager in the competition's history, after former Chelsea manager Andre Villas-Boas (33) in 2011.

2 – Ajax have only lost two of 10 games against Portuguese opponents since the inaugural European Cup. However, just two of these games have taken place this century.

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