Just when the Cleveland Browns thought they were in position to open the NFL season with a statement win, Patrick Mahomes did what Patrick Mahomes does.
The Kansas City Chiefs star threw for a pair of touchdowns in the fourth quarter as the reigning AFC champions edged the Browns 33-29 on Sunday.
Mahomes completed 27 of his 36 passes for 337 yards and three interceptions as the former MVP made more NFL history.
The 25-year-old broke the record for most passing yards in NFL history through first 50 games, while he also boasts the most passing touchdowns ever through the same amount of appearances.
Cleveland had built a 22-10 half-time lead, with Baker Mayfield directing three scoring drives that led to Nick Chubb finding the end zone twice and Jarvis Landry running in another touchdown before the break.
Mayfield finished 21 of 28 passing for 321 yards, but had one critical mistake late. With the Browns near midfield and just over a minute to play, the Chicago quarterback scrambled to avoid pressure before throwing a pass up for grabs to the left sideline. Mike Hughes leaped to intercept the ball and the Chiefs ran out the clock from there.
Mahomes, meanwhile, was poised as ever as he led the Chiefs to their ninth win in the last 11 games in which they trailed by double digits.
It started with a 14-play drive to open the second half, capped by an 11-yard TD pass to his favourite target Travis Kelce.
The signature moment, though, was a stunning 75-yard deep strike to Tyreek Hill that brought the Chiefs within two early in the fourth quarter.
The Browns botched a punt deep in their own territory on the ensuing drive and Mahomes hit Kelce for the go-ahead touchdown three plays later.
It was the kind of turnaround Cleveland fans have grown all too accustomed to over the years, particularly in season openers.
The Browns have not won in Week 1 since 2004 and are now 0-16-1 since.
Winston, Saints crush Packers
Aaron Rodgers dominated the headlines throughout the NFL offseason but he was upstaged in a big way as the season began.
Jameis Winston threw for five touchdowns as Rodgers and the Green Bay Packers were kept from the end zone altogether in a 38-3 New Orleans Saints rout.
Rodgers completed just 15 of 28 passes for 133 yards and threw two interceptions. He had only five interceptions all of last season on the way to being named NFL MVP for the third time.
Winston took over the starting role in New Orleans from another future Hall of Famer, the retired Drew Brees, and was brilliant at the Superdome. He completed 14 of 20 passes for 148 yards without an interception or a sack.
In a matchup of two young quarterbacks, Tua Tagovailoa got the better of his former Alabama team-mate Mac Jones as the Miami Dolphins edged the New England Patriots 17-16 on the road.
While the rookie Jones had the better numbers of the two with 29 of 39 passing, 281 yards, one touchdown and no interceptions, the Patriots repeatedly had to settle for field goals.
Tagovailoa, meanwhile, ran one touchdown in himself and threw for another in the third quarter that provided the eventual winning margin.