The Premier League fixture release for the 2021-22 has thrown up some intriguing opening-day clashes.

Champions Manchester City head to Tottenham, with the future of Harry Kane and speculation over which club he might be representing by August 14 still up in the air.

Arsenal are at newly promoted Brentford, while there is a familiar feel to Liverpool travelling to Championship winners Norwich City.

Manchester United v Leeds United is very much in the conversation when it comes to what might be the pick of the initial games, while Chelsea's quest to add domestic dominance to European glory begins against Crystal Palace.

Here, with help from Opta, Stats Perform looks at some of the landmark numbers thrown up by the big kick-off and who might be gunning for a piece of history this time around.

Chelsea to soar against the Eagles?

Still without a manager and facing a close season of extensive squad turnover, Palace certainly have a daunting assignment in prospect at Stamford Bridge against Thomas Tuchel's Champions League winners.

Chelsea boast the biggest opening-day win in Premier League history, a 6-0 thrashing of West Brom in August 2010.

That result replaced the previous most emphatic triumph by Liverpool, who won 6-1 away from home back in 1994. Their opponents? Crystal Palace.

Klopp and Salah send out another welcome party

For a third consecutive season, Liverpool will face a promoted team in their first match of the campaign, having thumped Norwich 4-1 at Anfield in 2019-20 before sharing a 4-3 thriller with Leeds last time around.

Mohamed Salah fired a hat-trick against Marcelo Bielsa's men – the ninth opening-day treble in the competition – and was also on target versus the Canaries.

Salah's six goals on the first weekend place him joint third in the Premier League's all-time standings, level with Leicester City's Jamie Vardy. Frank Lampard, Wayne Rooney and Alan Shearer (eight) have more matchday one goals than any other player.

Rooney's five assists leave him out in front on 13 goal involvements, ahead of Shearer and Teddy Sheringham (10).

More capital punishment from Sterling?

Alongside Salah, Raheem Sterling is the only other active Premier League star to have an opening-day hat-trick to his name, having claimed the matchball in Manchester City's 5-0 win at West Ham in 2019.

Overall, the England winger has five goals and two assists on matchday one, and Pep Guardiola's side will be looking to continue a habit of making flying starts.

City have won all of their opening day fixtures in Guardiola's previous five seasons in charge. Indeed, they have won each of their past 10 games on the opening weekend, dating back to a 4-0 triumph over newly promoted Swansea City in 2011.

However, the last time they failed to take an initial three points was in a 0-0 draw at Spurs in 2010. Additionally, in three visits to Tottenham Hotspur Stadium in all competitions since its 2019 opening, City have suffered three defeats and failed to score a goal.

Gunners must keep cool to avoid Bees sting

History is to repeat itself on a historic day for Brentford. Arsenal's visit will be their first top-flight game for 74 years, since a 1-0 defeat to the Gunners in May 1947.

Thomas Frank might be able to count on ill-discipline afflicting Mikel Arteta's side if Arsenal's previous efforts are anything to go by.

No team in Premier League history has collected as many as the north London club's six opening-day red cards, one more than Charlton Athletic – a fairly remarkable return given the Addicks were relegated in 2007 and are yet to return.

Jurgen Klopp believes dwindling confidence in front of goal is at the root of Liverpool's ongoing struggles this season, as opposed to bad luck.

Although their active defence of the title has long since ended, Liverpool could formally end their stint as Premier League champions by claiming a much-needed victory over rivals Manchester United at Old Trafford on Sunday.

If Manchester City beat Crystal Palace on Saturday and their neighbours lose to Klopp's men, Pep Guardiola's side will be crowned kings of England for the third time in the past four seasons.

That development might not be overly surprising, but the distance from which Liverpool have watched it unfold – having been the main counterpoint to City's pretentions of dominance over the previous three years – certainly has been.

The Reds are sixth in the table, four points shy of fourth-placed Chelsea with five games remaining heading into the weekend, meaning anything other than three points against United would make their chances of Champions League qualification increasingly remote.

Long-term injuries to key defenders Virgil van Dijk and Joe Gomez have taken a significant toll but a misfiring attack has been under the spotlight over recent weeks.

Firing blanks

In three consecutive draws against Real Madrid, Leeds United and Newcastle United, Liverpool had 54 shots – including efforts blocked, as per Opta – and scored twice.

"We had a really detailed look at all the situations that we created over the last seven or eight games just to get an overview," Klopp told Sky Sports. "It is not unlucky. There are moments where we are unlucky. But if you are unlucky so often there must be something else.

"Sometimes it sounds a little boring, but we know we have to improve. The one thing we have to keep working on is the finishing. We have to finish the situations off. We have created [many] chances in the last three games and scored twice. That is obviously not enough.

"The performance around that shows you that something was right in the game. We had really good spells, but the important moment is the last moment. We cannot expect it to change overnight but we will not stop working on it.

"It is not exactly the football of last year, maybe, but it is all fuelled by that one moment. Either you score or you don't score. We have to keep working. We don't have to change inside out, 360 degrees or whatever. We only have to improve and to make it click."

Mane and Firmino under pressure

Such problems were unforeseeable at Christmas after Liverpool routed Palace 7-0 to go clear at the top of the table.

In the 19 Premier League games since, Liverpool have scored 19 times despite amassing an expected goals (xG) figure of 30.3. An xG underperformance of -11.3 is comfortably the worst in the division over this period.

Mohamed Salah has scored seven times in the top flight since December 25 and remains in the hunt for the Golden Boot on 20, one shy of Harry Kane. However, his attacking allies Sadio Mane and Roberto Firmino have managed three and one in 17 appearances apiece since then.

Salah and Mane are converting those opportunities Opta classes as "big chances" at 23.5 and 23.1 per cent success rates over the period in question, with Firmino languishing on 12.5 after netting one out of eight.

Compared to the trio most likely to feature in United's forward line this weekend, the lack of efficiency is stark. Since Christmas Day, Marcus Rashford has put away 37.5 per cent of his big chances, with Mason Greenwood and Edinson Cavani snaffling 40 and 50 per cent respectively.

"We can see the boys are not confident enough in the moment," Klopp said. "They don't use their first touch. They want to make sure the ball is in the right position and then it is too late, the defender jumps in.

"There are a lot of things. After not scoring for a while, you do not use some situations for finishing. That is normal because we are not flying."

Big six appeal

Funnily enough, the Untied game might be just what Liverpool need.

Shelling points to the likes of Leeds and Newcastle, due to late equalisers from Diego Llorente and Joe Willock, has been symptomatic of their season.

In games between the Premier League's 'big six' this term, Liverpool have won five, drawn two and lost two to claim 17 points – a level-best points haul from those matches alongside City.

"It is about talking to them, helping them to find solutions," Klopp added. "You can do that in training. All that is fine but then the game starts and the first ball does not go in, the second ball does not go in and the third ball does not go in. It is like a wound that is bleeding again.

"That is what you can see on the pitch. But a missed chance is information. You have to use it. The things we did to get in the position were right, so do it again but just adapt a little bit. Keep going. Stay positive."

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